ARCHER FUSIONPLEX PAN SOLID TUMOR V2 PANEL
Gene Fusion Detection Testing for glioblastoma and other brain tumors
ARCHER FUSIONPLEX PAN SOLID TUMOR V2 PANEL
Gene Fusion Detection Testing for glioblastoma and other brain tumors
What is Archer fusionplex pan solid tumor v2 panel
The Archer FusionPlex Pan Solid Tumor v2 Panel is an RNA-based next-generation sequencing (NGS) test designed to detect gene fusions, splice variants, and expression imbalances across 137 cancer-related genes. It uses Anchored Multiplex PCR (AMP™) technology, which allows detection of known and novel fusions without prior knowledge of the fusion partner.
This panel is especially useful in solid tumors like glioblastoma, where the presence of oncogenic fusions and splicing events may guide targeted therapy or confirm diagnosis.
WHY IT MATTERS FOR GLIOBLASTOMA PATIENTS
For glioblastoma and other solid tumors, the information from this test is clinically valuable because:
- It can identify gene fusions that may be driving tumor growth.
- It can identify actionable gene fusions that predict response to targeted therapies (e.g., FGFR, NTRK inhibitors, etc.)
- It can help detect specific gene fusions enabling patients to enroll in targeted therapy trials.
- It reveals molecular mechanisms of tumorigenesis and resistance to treatment.
Fusion events are increasingly relevant as druggable targets across tumor types, including glioblastoma, where
treatments are limited.
Identify actionable fusions
It can identify gene fusions diriving tumor growth and pinpoint actionable mutations that guide treatment decisions.
Personalized treatment
It can expand targeted therapy treatment options (e.g., FGFR, NTRK inhibitors, etc.) based on the molecular features of a glioblastoma tumor.
Molecular mechanisms
It reveals molecular mechanisms of tumorigenesis and esistance
Clinical trials
It can help match patients to clinical trials based on specific fusion mutations.
"Fusion testing helped expand treatment options with targeted therapies for my patient."
- Provider, on Gene Fusion Detection Testing
TEST INFORMATIOn
Feature
DETAILS
| Sample | 8-10 FFPE scrolls or 10-20 unstained slides with 1 H & E |
| Turnaround Time | 10-14 business days |
| CPT Code | 81479 |
| Insurance | Covered by Medicare and major insurers |
